Month: June 2013

Stayin’ alive, stayin’ alive

oxicm Journals, Papers to be reviewed , , ,

Duration of resuscitation efforts and subsequent survival after in-hospital cardiac arrest

Zachary D. Goldberger, MD, MS, Paul S. Chan, MD, MSc, Robert A. Berg, MD, Steven L. Kronick, MD, MS, Colin R. Cooke, MD, MSc, Mingrui Lu, MPH, Mousumi Banerjee, PhD, Rodney A. Hayward, MD, Harlan M. Krumholz, MD SM, and Brahmajee K. Nallamothu, MD, MPH for the American Heart Association’s Get With the Guidelines®-Resuscitation (formerly, the National Registry of Cardiopulmonary Resuscitation) Investigators

Published in final edited form as:
Lancet. 2012 October 27; 380(9852): 1473–1481. doi:10.1016/S0140-6736(12)60862-9.

From Tobster:
Hi all,

Journal club this Friday deal with when to call time on resuscitation – does this tell us that we should be flogging the proverbial for better outcomes overall, or is it that, if we anticipate a better outcome, we’re more likely to resuscitate for longer? The paper is attached.

Cheers

Antimicrobial treatment – go hard or easy?

oxicm Journals, Papers reviewed, Papers to be reviewed , , ,

From Toby  T: 

Hi folks,

Journal club IS on this Friday: there has been a late change of presenter and paper – Dave will be presenting instead of Joy, and the new paper is attached below.  It examines antibiotic strategies in surgical ICU patients, and is well worth a read, if only to assuage the vexations of our forlorn micro colleagues on their daily antibug cull, with a felicitous allusion to the latest research from the Lancet, no less…

Cheers

Toby.

Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort study.

Hranjec T, Rosenberger LH, Swenson B, Metzger R, Flohr TR, Politano AD, Riccio LM, Popovsky KA, Sawyer RG.

Published in The Lancet Infect Dis. 2012 Oct;12(10):774-80. doi: 10.1016/S1473-3099(12)70151-2. Epub 2012 Aug 28.

Sticking metal in the head – is this a good thing?

oxicm Journals, Papers to be reviewed , ,

A Trial of Intracranial-Pressure Monitoring in Traumatic Brain Injury 

Randall M. Chesnut, M.D., Nancy Temkin, Ph.D., Nancy Carney, Ph.D., Sureyya Dikmen, Ph.D., Carlos Rondina, M.D., Walter Videtta, M.D., Gustavo Petroni, M.D., Silvia Lujan, M.D., Jim Pridgeon, M.H.A., Jason Barber, M.S.,
Joan Machamer, M.A., Kelley Chaddock, B.A., Juanita M. Celix, M.D., Marianna Cherner, Ph.D., and Terence Hendrix, B.A

Department of Neurological Surgery, University of Washington, Harborview Medical Center, Seattle, WA 98104, USA

Published in The N Engl J Med. 2012 Dec 27;367(26):2471-81.

doi: 10.1056/NEJMoa1207363. Epub 2012 Dec 12.

Controversial study, this. Would it have had ethical approval if it had been conducted in the US or the UK? Does it change practice given the findings? Find out the answers to these and more questions… this will be presented by James H on Friday 14th at the usual time.

Et tu, Brute? The CESAR trial

oxicm Journals, Papers reviewed , , ,

Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial. 

Giles J Peek, Miranda Mugford, Ravindranath Tiruvoipati, Andrew Wilson, Elizabeth Allen, Mariamma M Thalanany, Clare L Hibbert, Ann Truesdale, Felicity Clemens, Nicola Cooper, Richard K Firmin, Diana Elbourne, for the CESAR trial collaboration.

Published in The Lancet, Volume 374, Issue 9698, Pages 1351 – 1363, 17 October 2009
doi:10.1016/S0140-6736(09)61069-2

This will be presented by Caroline on Friday 7th.

Amusing.
Amusing.